Subtle genetic modifications transformed an enteropathogen into a flea-borne pathogen: Table 1.
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منابع مشابه
Subtle genetic modifications transformed an enteropathogen into a flea-borne pathogen.
Yersinia pestis is the etiological agent of plague, one of the most devastating diseases in human history. Because of the identification of the plague bacillus, the understanding of its epidemiological cycle, and the advent of efficient antibiotic therapies, the death toll due to the plague has dramatically decreased over the last 100 y. However, this disease has never been eradicated, and beca...
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Rickettsia felis is an emerging insect-borne rickettsial pathogen and the causative agent of flea-borne spotted fever. First described as a human pathogen from the USA in 1991, R. felis is now identified throughout the world and considered a common cause of fever in Africa. The cosmopolitan distribution of this pathogen is credited to the equally widespread occurrence of cat fleas (Ctenocephali...
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Ecologic and economic factors, as well as changes in human behavior, have resulted in the emergence of new and the reemergence of existing but forgotten infectious diseases during the past 20 years. Flea-borne disease organisms (e.g., Yersinia pestis, Rickettsia typhi, R. felis, and Bartonella henselae) are widely distributed throughout the world in endemic-disease foci, where components of the...
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Rickettsia typhi and Rickettsia felis are flea-borne rickettsiae that are distributed throughout the world. This mini-review outlines the ecology and epidemiology of flea-borne rickettsioses; highlights important clinical, diagnostic, and therapeutic considerations; and discusses areas of uncertainty regarding Rickettsia felis and other rickettsiae harbored by fleas.
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2014
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.1421887112